JOHNSON JOHNSON, ARVO 2024에서 망막 질환 치료 변혁 약속 강조

존슨앤드존슨, ARVO 2024 연례 회의서 안과 질환 연구 성과 발표 존슨앤드존슨(JNJ)은 오는 5월 5일부터 9일까지 시애틀에서 개최되는 미국 안과 연구 학회(ARVO) 2024 연례 회의에서 8건의 회사 후원 발표를 진행한다고 밝혔습니다. 이번 학회에서 존슨앤드존슨은 두 건의 구두 발표를 통해 혁신적인 연구 결과를 공유할 예정입니다. 첫 번째 발표는 유전성 망막 질환(IRDs) 환자의 조기 유전자 검사가 갖는 경제적 가치를 실제 데이터를 기반으로 분석한 내용을 다룹니다. IRDs는 심각한 시력 손상을 유발할 수 있는 희귀 안과 질환입니다. (발표 번호: Abstract #2154) 두 번째 구두 발표는 노년성 황반 변성(AMD)의 후기 및 중증 형태인 지리적 위축(GA)의 전구체를 측정하는 데 있어 자동 딥러닝 기반 알고리즘의 역할을 평가합니다. (발표 번호: Abstract #2770) 또한, 존슨앤드존슨은 이번 학회에서 최초로 개발된 관찰적, 비개입적 글로벌 IRD 등록 시스템인 EYE-RD Global Registry를 선보일 예정입니다. 이 등록 시스템은 X-연관 망막색소변성증과 같이 전 세계적으로 약 4만 명 중 1명에게 영향을 미치는 것으로 추정되는 희귀 IRD 환자들의 유전자 검사 관련 임상 정보를 환자, 의료 제공자, 보험사, 연구자들에게 보다 쉽게 접근할 수 있도록 지원합니다. 이 등록 시스템은 질병 진행 및 환자 경험에 대한 보다 포괄적인 통찰력을 수집함으로써 IRDs 분야의 지식 격차를 해소하는 데 기여할 것으로 기대됩니다. 존슨앤드존슨의 Hideo Makimura 박사(부사장, 특수 안과 연구 개발 총괄)는 "존슨앤드존슨은 실명을 예방하고, 최고의 과학을 활용하여 실명 유발 망막 질환을 앓고 있는 환자들에게 해결책을 제공하기 위해 최선을 다하고 있습니다"라며, "ARVO 2024에서 발표될 이러한 데이터는 전 세계 환자들의 시력을 보존하고 회복시키는 혁신적인 신규 치료법을 제공하려는 우리의 노력을 보여줍니다"라고 말했습니다. 두 건의 구두 발표에서 발표될 주요 결과는 다음과 같습니다. 유전성 망막 영양증 진단에서 조기 유전자 검사의 경제적 가치 (Abstract #2154) - 유전자 검사가 지연된 환자들은 조기 유전자 검사를 받은 환자들에 비해 훨씬 높은 의료 비용을 부담했습니다. (총 비용: 각각 $76,838 대 $13,084) - 유전자 검사는 인식 부족이나 비용 문제로 인해 지연되는 경우가 많습니다. 이번 데이터는 IRD 진단을 개선하고 전반적인 의료 비용을 절감하는 데 조기 검사의 중요성을 강조합니다. 스펙트럼 도메인 광간섭 단층 촬영(SD-OCT) 영상에서 cRORA 및 광수용체 손실의 자동 딥러닝 기반 알고리즘 (Abstract #2770) - 환자별 지리적 위축(GA)의 느리고 가변적인 진행 속도로 인해 임상 시험에서 치료 효과를 측정하는 것이 어려울 수 있으며, 이는 종종 긴 시험 기간과 많은 수의 피험자를 필요로 하여 잠재적인 신규 치료법의 가용성을 지연시킬 수 있습니다. - 다중 SD-OCT 영상 바이오마커에 대한 자동 딥러닝 기반 분할은 질병 진행을 정량화하고 예측하는 데 시간과 비용을 절약하는 효과적인 방법을 제공할 수 있으며, 임상 시험에서 치료 효과를 더 신속하게 결정하는 데 도움이 될 수 있습니다. ARVO 연례 회의에서 발표될 존슨앤드존슨 후원 초록 전체 목록은 다음과 같습니다. 초록은 ARVO 웹사이트에서도 확인할 수 있습니다. 발표/포스터 번호 | 제목 | 초록 번호 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